Transcribed genes |
Gene | Score | GO annotation |
Ptafr | 2 |
BP MF CC |
biological_process | - G-protein coupled receptor protein signaling pathway
- chemotaxis
- cytokine production
- inflammatory response
more... - inositol trisphosphate biosynthetic process
- lipopolysaccharide-mediated signaling pathway
- pattern recognition receptor signaling pathway
- phosphatidylinositol-mediated signaling
- response to lipopolysaccharide
less...
|
| cellular_component | - integral to membrane
- intracellular membrane-bounded organelle
- membrane
- nucleolus
more... - nucleus
- plasma membrane
less...
|
| | |
Csf1r | 2 |
BP MF CC |
biological_process | - cell proliferation
- positive regulation of osteoclast differentiation
- skeletal muscle tissue development
- transmembrane receptor protein tyrosine kinase signaling pathway
more...
|
| cellular_component | - cellular_component
- integral to membrane
- membrane
- plasma membrane
more... - receptor complex
less...
|
| molecular_function | - ATP binding
- cytokine binding
- molecular_function
- nucleotide binding
more... - protein homodimerization activity
- receptor activity
- transmembrane receptor protein tyrosine kinase activity
less...
|
| |
Mmp12 | 2 |
BP MF CC |
biological_process | - metabolic process
- positive regulation of epithelial cell proliferation
- positive regulation of epithelial cell proliferation involved in wound healing
- proteolysis
more... - response to chemical stimulus
- response to drug
- wound healing, spreading of epidermal cells
less...
|
| cellular_component | - extracellular matrix
- extracellular region
- proteinaceous extracellular matrix
|
| molecular_function | - calcium ion binding
- metal ion binding
- metalloendopeptidase activity
- peptidase activity
more... - zinc ion binding
less...
|
| |
Sox9 | 2 |
BP MF CC |
biological_process | - Sertoli cell development
- Sertoli cell differentiation
- astrocyte fate commitment
- cAMP-mediated signaling
more... - cartilage condensation
- cartilage development
- cell differentiation
- cell fate commitment
- cell fate specification
- cellular response to retinoic acid
- cellular response to transforming growth factor beta stimulus
- chondrocyte development
- chondrocyte differentiation involved in endochondral bone morphogenesis
- chondrocyte hypertrophy
- chromatin remodeling
- cochlea morphogenesis
- endocardial cushion morphogenesis
- endochondral bone morphogenesis
- endocrine pancreas development
- epithelial cell proliferation involved in prostatic bud elongation
- epithelial to mesenchymal transition
- extracellular matrix organization
- hair follicle development
- heart development
- heart valve development
- heart valve formation
- heart valve morphogenesis
- intestinal epithelial structure maintenance
- intrahepatic bile duct development
- male germ-line sex determination
- male gonad development
- male sex determination
- metanephric nephron tubule formation
- morphogenesis of a branching epithelium
- negative regulation of apoptosis
- negative regulation of biomineral tissue development
- negative regulation of bone mineralization
- negative regulation of canonical Wnt receptor signaling pathway
- negative regulation of cell proliferation
- negative regulation of chondrocyte differentiation
- negative regulation of epithelial cell proliferation
- negative regulation of immune system process
- negative regulation of myoblast differentiation
- negative regulation of ossification
- negative regulation of photoreceptor cell differentiation
- negative regulation of transcription, DNA-dependent
- neural crest cell development
- nucleosome assembly
- oligodendrocyte differentiation
- otic vesicle formation
- positive regulation of branching involved in ureteric bud morphogenesis
- positive regulation of cartilage development
- positive regulation of cell proliferation
- positive regulation of cell proliferation involved in heart morphogenesis
- positive regulation of chondrocyte differentiation
- positive regulation of epithelial cell differentiation
- positive regulation of epithelial cell migration
- positive regulation of epithelial cell proliferation
- positive regulation of gene expression
- positive regulation of kidney development
- positive regulation of male gonad development
- positive regulation of mesenchymal cell proliferation
- positive regulation of mesenchymal stem cell differentiation
- positive regulation of phosphatidylinositol 3-kinase cascade
- positive regulation of protein catabolic process
- positive regulation of protein phosphorylation
- positive regulation of transcription from RNA polymerase II promoter
- positive regulation of transcription, DNA-dependent
- prostate gland morphogenesis
- protein complex assembly
- protein kinase B signaling cascade
- regulation of apoptosis
- regulation of cell adhesion
- regulation of cell cycle process
- regulation of cell differentiation
- regulation of cell proliferation
- regulation of cell proliferation involved in tissue homeostasis
- regulation of transcription from RNA polymerase II promoter
- regulation of transcription, DNA-dependent
- renal vesicle induction
- retina development in camera-type eye
- retinal rod cell differentiation
- signal transduction
- skeletal system development
- somatic stem cell maintenance
- spermatogenesis
- tissue homeostasis
- transcription, DNA-dependent
- ureter morphogenesis
less...
|
| cellular_component | - chromatin remodeling complex
- nucleus
- protein complex
|
| molecular_function | - DNA binding
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
- beta-catenin binding
- chromatin binding
more... - core promoter sequence-specific DNA binding
- enhancer binding
- protein binding
- protein kinase A catalytic subunit binding
- protein kinase activity
- sequence-specific DNA binding
- sequence-specific DNA binding transcription factor activity
- sequence-specific distal enhancer binding RNA polymerase II transcription factor activity
- transcription regulatory region DNA binding
- transcription regulatory region sequence-specific DNA binding
less...
|
| |
Glul | 2 |
BP MF CC |
biological_process | - ammonia assimilation cycle
- cell proliferation
- glutamate metabolic process
- glutamine biosynthetic process
more... - neurotransmitter metabolic process
- nitrogen compound metabolic process
- positive regulation of epithelial cell proliferation
- positive regulation of insulin secretion
- positive regulation of synaptic transmission, glutamatergic
- protein homooligomerization
- response to glucose stimulus
less...
|
| cellular_component | - Golgi apparatus
- axon terminus
- cell projection
- cytoplasm
more... - intracellular
- microsome
- mitochondrion
- perikaryon
- protein complex
- rough endoplasmic reticulum
- soluble fraction
- synaptosome
less...
|
| molecular_function | - ATP binding
- dynein light chain binding
- glutamate binding
- glutamate decarboxylase activity
more... - glutamate-ammonia ligase activity
- ligase activity
- lyase activity
- magnesium ion binding
- manganese ion binding
- nucleotide binding
less...
|
| |
Cd82 | 2 |
BP MF CC |
| cellular_component | - cellular_component
- integral to membrane
- membrane
|
| | |
Cd74 | 2 |
BP MF CC |
biological_process | - activation of MAPK activity
- antigen processing and presentation
- antigen processing and presentation of exogenous peptide antigen via MHC class II
- cell proliferation
more... - chaperone mediated protein folding requiring cofactor
- cytokine-mediated signaling pathway
- defense response
- immune response
- immunoglobulin mediated immune response
- intracellular protein transport
- macrophage migration inhibitory factor signaling pathway
- negative regulation of DNA damage response, signal transduction by p53 class mediator
- negative regulation of T cell differentiation
- negative regulation of apoptosis
- negative regulation of mature B cell apoptosis
- negative regulation of peptide secretion
- negative thymic T cell selection
- positive regulation of B cell proliferation
- positive regulation of ERK1 and ERK2 cascade
- positive regulation of T cell differentiation
- positive regulation of chemokine (C-X-C motif) ligand 2 production
- positive regulation of cytokine-mediated signaling pathway
- positive regulation of dendritic cell antigen processing and presentation
- positive regulation of fibroblast proliferation
- positive regulation of macrophage cytokine production
- positive regulation of neutrophil chemotaxis
- positive regulation of peptidyl-tyrosine phosphorylation
- positive regulation of type 2 immune response
- positive thymic T cell selection
- prostaglandin biosynthetic process
- protein complex assembly
- signal transduction
less...
|
| cellular_component | - Golgi apparatus
- MHC class II protein complex
- NOS2-CD74 complex
- cell surface
more... - endoplasmic reticulum
- external side of plasma membrane
- integral to membrane
- late endosome
- lysosome
- macrophage migration inhibitory factor receptor complex
- multivesicular body
- plasma membrane
- receptor complex
- vacuole
less...
|
| | |
Bach1 | 2 |
BP MF CC |
biological_process | - negative regulation of transcription from RNA polymerase II promoter
- regulation of transcription from RNA polymerase II promoter in response to stress
- regulation of transcription involved in G1/S phase of mitotic cell cycle
- regulation of transcription involved in G2/M-phase of mitotic cell cycle
more... - regulation of transcription, DNA-dependent
less...
|
| | | |
S100a9 | 2 |
BP MF CC |
biological_process | - actin cytoskeleton reorganization
- chemotaxis
- chronic inflammatory response
- leukocyte chemotaxis
more... - regulation of integrin biosynthetic process
- response to ethanol
- response to lipopolysaccharide
- response to zinc ion
less...
|
| | molecular_function | - calcium ion binding
- molecular_function
|
| |
Hmox1 | 2 |
BP MF CC |
biological_process | - DNA damage response, signal transduction resulting in induction of apoptosis
- angiogenesis
- anti-apoptosis
- cell death
more... - cellular response to hypoxia
- cellular response to nutrient
- erythrocyte homeostasis
- heme catabolic process
- heme oxidation
- intracellular signal transduction
- iron ion homeostasis
- negative regulation of DNA binding
- negative regulation of cell proliferation
- negative regulation of mast cell cytokine production
- negative regulation of mast cell degranulation
- negative regulation of neuron apoptosis
- negative regulation of sequence-specific DNA binding transcription factor activity
- negative regulation of smooth muscle cell proliferation
- oxidation-reduction process
- phospholipid metabolic process
- positive regulation of I-kappaB kinase/NF-kappaB cascade
- positive regulation of angiogenesis
- positive regulation of anti-apoptosis
- positive regulation of smooth muscle cell proliferation
- protein homooligomerization
- regulation of blood pressure
- regulation of sequence-specific DNA binding transcription factor activity
- regulation of transcription from RNA polymerase II promoter in response to oxidative stress
- response to estrogen stimulus
- response to hydrogen peroxide
- response to hypoxia
- response to nicotine
- response to oxidative stress
- response to stimulus
- signal transduction
- small GTPase mediated signal transduction
- wound healing involved in inflammatory response
less...
|
| | molecular_function | - enzyme binding
- heme binding
- heme oxygenase (decyclizing) activity
- metal ion binding
more... - oxidoreductase activity
- phospholipase D activity
- protein binding
- protein homodimerization activity
- signal transducer activity
less...
|
| |
Optn | 2 |
BP MF CC |
| cellular_component | - Golgi apparatus
- cytoplasm
- cytoplasmic membrane-bounded vesicle
- perinuclear region of cytoplasm
more... - trans-Golgi network
less...
|
| molecular_function | - protein C-terminus binding
|
| |
Pdgfrb | 2 |
BP MF CC |
biological_process | - adrenal gland development
- aorta morphogenesis
- cardiac myofibril assembly
- cell chemotaxis
more... - glycosaminoglycan biosynthetic process
- hemopoiesis
- in utero embryonic development
- inner ear development
- intracellular protein kinase cascade
- kidney development
- metanephric S-shaped body morphogenesis
- metanephric comma-shaped body morphogenesis
- metanephric glomerular capillary formation
- metanephric glomerular mesangial cell proliferation involved in metanephros development
- metanephric glomerulus morphogenesis
- metanephric mesenchymal cell migration
- metanephric mesenchyme development
- nitrogen compound metabolic process
- peptidyl-tyrosine phosphorylation
- platelet-derived growth factor receptor signaling pathway
- platelet-derived growth factor receptor-beta signaling pathway
- positive regulation of DNA biosynthetic process
- positive regulation of ERK1 and ERK2 cascade
- positive regulation of MAP kinase activity
- positive regulation of anti-apoptosis
- positive regulation of calcium ion import
- positive regulation of cell migration
- positive regulation of cell proliferation
- positive regulation of chemotaxis
- positive regulation of collagen biosynthetic process
- positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
- positive regulation of mitosis
- positive regulation of phosphatidylinositol 3-kinase cascade
- positive regulation of reactive oxygen species metabolic process
- positive regulation of smooth muscle cell migration
- positive regulation of smooth muscle cell proliferation
- protein autophosphorylation
- protein phosphorylation
- regulation of actin cytoskeleton organization
- regulation of peptidyl-tyrosine phosphorylation
- response to estradiol stimulus
- response to estrogen stimulus
- response to fluid shear stress
- response to hydrogen peroxide
- response to hyperoxia
- response to lipid
- response to organic cyclic compound
- response to retinoic acid
- response to toxin
- retina vasculature development in camera-type eye
- signal transduction
- skeletal system morphogenesis
- smooth muscle cell chemotaxis
- smooth muscle tissue development
- tissue homeostasis
- transforming growth factor beta receptor signaling pathway
- wound healing
less...
|
| | molecular_function | - ATP binding
- growth factor binding
- kinase activity
- nucleotide binding
more... - phosphatidylinositol 3-kinase binding
- platelet-derived growth factor beta-receptor activity
- platelet-derived growth factor binding
- platelet-derived growth factor receptor binding
- platelet-derived growth factor-activated receptor activity
- protein binding
- protein kinase activity
- protein tyrosine kinase activity
- receptor activity
- receptor binding
- signal transducer activity
- vascular endothelial growth factor-activated receptor activity
less...
|
| |
Cyp7b1 | 2 |
BP MF CC |
biological_process | - bile acid biosynthetic process
- cholesterol metabolic process
- circadian rhythm
- memory
more... - negative regulation of estrogen receptor signaling pathway
- positive regulation of epithelial cell proliferation
- prostate gland epithelium morphogenesis
- response to cAMP
- response to drug
- steroid metabolic process
less...
|
| cellular_component | - cellular_component
- endoplasmic reticulum
- endoplasmic reticulum membrane
- membrane
more... - microsome
less...
|
| | |
Tnfsf12 | 2 |
BP MF CC |
| cellular_component | - extracellular region
- perinuclear region of cytoplasm
|
| | |
Klf6 | 2 |
BP MF CC |
biological_process | - cytokine-mediated signaling pathway
- positive regulation of transcription from RNA polymerase II promoter
- transcription, DNA-dependent
- wound healing
more...
|
| cellular_component | - cytoplasm
- intracellular
- nucleus
|
| molecular_function | - DNA binding
- double-stranded DNA binding
- metal ion binding
- sequence-specific DNA binding transcription factor activity
more... - zinc ion binding
less...
|
| |
Itga4 | 2 |
BP MF CC |
biological_process | - blood vessel remodeling
- cell adhesion
- cell migration
- chorio-allantoic fusion
more... - face development
- heart development
- heterophilic cell-cell adhesion
- integrin-mediated signaling pathway
- leukocyte cell-cell adhesion
less...
|
| cellular_component | - cell surface
- external side of plasma membrane
- integral to membrane
- integrin complex
more... - membrane
- plasma membrane
less...
|
| molecular_function | - fibronectin binding
- identical protein binding
- receptor activity
|
| |
Cxcl13 | 2 |
BP MF CC |
biological_process | - B cell chemotaxis
- activation of Rap GTPase activity
- cell-cell signaling
- defense response to bacterium
more... - elevation of cytosolic calcium ion concentration
- endothelial cell chemotaxis to fibroblast growth factor
- immune response
- lymph node development
- lymphocyte chemotaxis across high endothelial venule
- positive regulation of T cell chemotaxis
- positive regulation of cell-cell adhesion mediated by integrin
- positive regulation of integrin activation
- signal transduction
less...
|
| | molecular_function | - CCR10 chemokine receptor binding
- CXCR3 chemokine receptor binding
- CXCR5 chemokine receptor binding
- chemokine activity
more... - fibroblast growth factor 2 binding
- heparin binding
- protein heterodimerization activity
- receptor agonist activity
less...
|
| |
Mmp7 | 2 |
BP MF CC |
biological_process | - antibacterial peptide secretion
- collagen catabolic process
- defense response to Gram-negative bacterium
- defense response to Gram-positive bacterium
more... - defense response to bacterium
- metabolic process
- proteolysis
- regulation of cell proliferation
- response to drug
less...
|
| cellular_component | - extracellular region
- proteinaceous extracellular matrix
|
| molecular_function | - metal ion binding
- metalloendopeptidase activity
- peptidase activity
- zinc ion binding
more...
|
| |
Icam1 | 2 |
BP MF CC |
biological_process | - T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
- T cell antigen processing and presentation
- adhesion to symbiont
- cell adhesion
more... - cell adhesion mediated by integrin
- cell aging
- cell-cell adhesion
- cellular response to alkaloid
- cellular response to glucose stimulus
- cellular response to hypoxia
- cellular response to interleukin-1
- cellular response to lipopolysaccharide
- cellular response to nutrient levels
- cellular response to organic substance
- cellular response to tumor necrosis factor
- leukocyte cell-cell adhesion
- leukocyte migration
- membrane to membrane docking
- negative regulation of calcium ion transport
- ovarian follicle development
- positive regulation of NF-kappaB transcription factor activity
- positive regulation of cellular extravasation
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vasoconstriction
- regulation of cell adhesion
- regulation of cell shape
- response to amino acid stimulus
- response to amphetamine
- response to copper ion
- response to drug
- response to ethanol
- response to gonadotropin stimulus
- response to hypoxia
- response to ionizing radiation
- response to lipopolysaccharide
- response to organic cyclic compound
- response to sulfur dioxide
- virion attachment, binding of host cell surface receptor
less...
|
| | molecular_function | - cell surface binding
- integrin binding
- protein complex binding
|
| |
Ndrg1 | 2 |
BP MF CC |
biological_process | - cellular response to hypoxia
- mast cell activation
- peripheral nervous system myelin maintenance
|
| cellular_component | - cytoplasm
- microtubule cytoskeleton
- nucleus
|
| | |
Fgr | 2 |
BP MF CC |
biological_process | - biological_process
- defense response to Gram-positive bacterium
- integrin-mediated signaling pathway
- peptidyl-tyrosine phosphorylation
more...
|
| cellular_component | - cytoskeleton
- cytosol
- plasma membrane
|
| | |
Dmbt1 | 2 |
BP MF CC |
biological_process | - blastocyst development
- cell differentiation
- inner cell mass cell proliferation
- multicellular organismal development
more... - positive regulation of epithelial cell differentiation
- protein transport
- response to estrogen stimulus
- response to organic substance
- response to wounding
- tissue regeneration
less...
|
| cellular_component | - cytoplasm
- cytoplasmic vesicle
- extracellular matrix
- extracellular region
more... - extrinsic to membrane
- integral to membrane
- intracellular
- membrane
- phagocytic vesicle membrane
- proteinaceous extracellular matrix
- transport vesicle membrane
- zymogen granule membrane
less...
|
| molecular_function | - Gram-negative bacterial cell surface binding
- Gram-positive bacterial cell surface binding
- molecular_function
- scavenger receptor activity
more... - zymogen binding
less...
|
| |
Mmp13 | 2 |
BP MF CC |
biological_process | - bone mineralization
- cartilage development
- collagen catabolic process
- embryonic hindlimb morphogenesis
more... - metabolic process
- ossification
- peptide catabolic process
- proteolysis
- receptor internalization
- response to estrogen stimulus
- response to hypoxia
- response to mechanical stimulus
less...
|
| | | |
Vav1 | 2 |
BP MF CC |
biological_process | - T cell activation
- cell development
- immune response
- immune response-regulating cell surface receptor signaling pathway
more... - integrin-mediated signaling pathway
- intracellular signal transduction
- phagocytosis
- positive regulation of cell adhesion
- regulation of GTPase activity
- regulation of Rho protein signal transduction
less...
|
| | molecular_function | - Rac guanyl-nucleotide exchange factor activity
- Rho guanyl-nucleotide exchange factor activity
- guanyl-nucleotide exchange factor activity
- metal ion binding
more...
|
| |
Bhlhe40 | 2 |
BP MF CC |
| cellular_component | - Golgi apparatus
- nucleolus
- nucleus
|
| | |
Cd83 | 2 |
BP MF CC |
| cellular_component | - external side of plasma membrane
|
| | |
Itgam | 2 |
BP MF CC |
| cellular_component | - cell surface
- external side of plasma membrane
- integral to membrane
- nucleus
more...
|
| | |
Aldh1a3 | 2 |
BP MF CC |
biological_process | - embryonic camera-type eye development
- embryonic eye morphogenesis
- face development
- kidney development
more... - nucleus accumbens development
- olfactory pit development
- optic cup morphogenesis involved in camera-type eye development
- oxidation-reduction process
- pituitary gland development
- positive regulation of apoptosis
- response to drug
- retinal metabolic process
- retinoic acid biosynthetic process
- retinoic acid metabolic process
less...
|
| | | |
Cdkn1a | 2 |
BP MF CC |
biological_process | - DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
- G1/S transition of mitotic cell cycle
- G2/M transition of mitotic cell cycle
- Ras protein signal transduction
more... - cell cycle
- cell cycle arrest
- cellular response to extracellular stimulus
- cellular response to ionizing radiation
- cellular senescence
- negative regulation of apoptosis
- negative regulation of cell growth
- negative regulation of cell proliferation
- negative regulation of cyclin-dependent protein kinase activity
- negative regulation of gene expression
- negative regulation of phosphorylation
- organ regeneration
- positive regulation of B cell proliferation
- positive regulation of anti-apoptosis
- positive regulation of fibroblast proliferation
- positive regulation of programmed cell death
- positive regulation of reactive oxygen species metabolic process
- regulation of DNA biosynthetic process
- regulation of cell cycle
- regulation of cyclin-dependent protein kinase activity
- regulation of mitotic cell cycle
- regulation of protein import into nucleus, translocation
- response to DNA damage stimulus
- response to UV
- response to arsenic-containing substance
- response to corticosterone stimulus
- response to drug
- response to glucocorticoid stimulus
- response to hyperoxia
- response to organic cyclic compound
- response to organic nitrogen
- response to organic substance
- response to toxin
less...
|
| cellular_component | - PCNA-p21 complex
- cyclin-dependent protein kinase holoenzyme complex
- cytoplasm
- cytosol
more... - nucleoplasm
- nucleus
less...
|
| | |
Il1b | 2 |
BP MF CC |
biological_process | - activation of MAPK activity
- aging
- anti-apoptosis
- cellular response to drug
more... - cellular response to mechanical stimulus
- cellular response to organic substance
- chronic inflammatory response to antigenic stimulus
- cytokine-mediated signaling pathway
- elevation of cytosolic calcium ion concentration
- fever generation
- immune response
- inflammatory response
- interleukin-1 beta production
- learning or memory
- leukocyte migration
- memory
- negative regulation of MAP kinase activity
- negative regulation of adiponectin secretion
- negative regulation of cell proliferation
- negative regulation of glucose transport
- negative regulation of glutamate secretion
- negative regulation of insulin receptor signaling pathway
- negative regulation of lipid catabolic process
- negative regulation of lipid metabolic process
- neutrophil chemotaxis
- ovulation
- positive regulation of ERK1 and ERK2 cascade
- positive regulation of I-kappaB kinase/NF-kappaB cascade
- positive regulation of JNK cascade
- positive regulation of JUN kinase activity
- positive regulation of NF-kappaB import into nucleus
- positive regulation of NF-kappaB transcription factor activity
- positive regulation of T cell proliferation
- positive regulation of angiogenesis
- positive regulation of apoptosis
- positive regulation of calcidiol 1-monooxygenase activity
- positive regulation of cell division
- positive regulation of chemokine biosynthetic process
- positive regulation of fever generation
- positive regulation of gene expression
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of interferon-gamma production
- positive regulation of interleukin-2 biosynthetic process
- positive regulation of interleukin-6 biosynthetic process
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of lipid catabolic process
- positive regulation of membrane protein ectodomain proteolysis
- positive regulation of mitosis
- positive regulation of monocyte chemotactic protein-1 production
- positive regulation of myosin light chain kinase activity
- positive regulation of nitric oxide biosynthetic process
- positive regulation of prostaglandin secretion
- positive regulation of protein phosphorylation
- positive regulation of sequence-specific DNA binding transcription factor activity
- positive regulation of stress-activated MAPK cascade
- positive regulation of transcription from RNA polymerase II promoter
- positive regulation vascular endothelial growth factor production
- regulation of I-kappaB kinase/NF-kappaB cascade
- regulation of insulin secretion
- response to ATP
- response to L-ascorbic acid
- response to chemical stimulus
- response to drug
- response to estradiol stimulus
- response to gamma radiation
- response to glucocorticoid stimulus
- response to heat
- response to hypoxia
- response to lipopolysaccharide
- response to morphine
- response to nutrient
- response to organic cyclic compound
- response to organic nitrogen
- response to ozone
- response to vitamin D
- sequestering of triglyceride
- social behavior
- wound healing
less...
|
| cellular_component | - extracellular region
- extracellular space
- stored secretory granule
- vesicle
more...
|
| molecular_function | - cytokine activity
- growth factor activity
- interleukin-1 receptor binding
- protein domain specific binding
more...
|
| |
C1s | 2 |
BP MF CC |
|
Cd79a | 2 |
BP MF CC |
| cellular_component | - B cell receptor complex
- external side of plasma membrane
- membrane
- membrane raft
more... - multivesicular body
less...
|
| molecular_function | - transmembrane signaling receptor activity
|
| |
Sod2 | 2 |
BP MF CC |
biological_process | - age-dependent response to oxidative stress
- age-dependent response to reactive oxygen species
- aging
- anti-apoptosis
more... - apoptosis
- cellular response to ethanol
- detection of oxygen
- erythrophore differentiation
- glutathione metabolic process
- heart development
- hemopoiesis
- hydrogen peroxide biosynthetic process
- hydrogen peroxide metabolic process
- iron ion homeostasis
- liver development
- locomotory behavior
- mitochondrion organization
- negative regulation of apoptosis
- negative regulation of cell proliferation
- negative regulation of fat cell differentiation
- negative regulation of fibroblast proliferation
- negative regulation of neuron apoptosis
- neuron development
- oxidation-reduction process
- oxygen homeostasis
- positive regulation of nitric oxide biosynthetic process
- post-embryonic development
- protein homooligomerization
- protein homotetramerization
- regulation of blood pressure
- regulation of catalytic activity
- regulation of mitochondrial membrane potential
- regulation of transcription from RNA polymerase II promoter
- release of cytochrome c from mitochondria
- removal of superoxide radicals
- respiratory electron transport chain
- response to L-ascorbic acid
- response to activity
- response to axon injury
- response to cadmium ion
- response to drug
- response to electrical stimulus
- response to gamma radiation
- response to hydrogen peroxide
- response to hyperoxia
- response to hypoxia
- response to lipopolysaccharide
- response to manganese ion
- response to nutrient levels
- response to oxidative stress
- response to reactive oxygen species
- response to selenium ion
- response to silicon dioxide
- response to stress
- response to superoxide
- response to zinc ion
- sensory perception of sound
- superoxide anion generation
- superoxide metabolic process
- vasodilation
- vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure
less...
|
| cellular_component | - cytoplasm
- mitochondrial inner membrane
- mitochondrial nucleoid
- mitochondrion
more... - soluble fraction
less...
|
| | |
Lyl1 | 2 |
BP MF CC |
biological_process | - B cell differentiation
- biological_process
- blood vessel maturation
- definitive hemopoiesis
more... - positive regulation of transcription, DNA-dependent
- regulation of transcription, DNA-dependent
less...
|
| cellular_component | - cellular_component
- nucleus
|
| molecular_function | - DNA binding
- molecular_function
|
| |
Alcam | 2 |
BP MF CC |
biological_process | - axon guidance
- cell adhesion
- motor axon guidance
|
| cellular_component | - axon
- external side of plasma membrane
- integral to membrane
- membrane
more... - neuronal cell body
less...
|
| | |
Tf | 2 |
BP MF CC |
biological_process | - SMAD protein signal transduction
- acute-phase response
- cellular iron ion homeostasis
- ferric iron transport
more... - ion transport
- iron ion transport
- positive regulation of myelination
- response to hypoxia
- response to organic cyclic compound
- small GTPase mediated signal transduction
- transferrin transport
less...
|
| cellular_component | - apical plasma membrane
- basal part of cell
- basal plasma membrane
- basement membrane
more... - coated pit
- cytoplasmic membrane-bounded vesicle
- early endosome
- endocytic vesicle
- endosome
- endosome membrane
- extracellular region
- extracellular space
- late endosome
- perinuclear region of cytoplasm
- recycling endosome
- stored secretory granule
less...
|
| molecular_function | - ferric iron binding
- ferric iron transmembrane transporter activity
- metal ion binding
|
| |
Wnt4 | 2 |
BP MF CC |
biological_process | - T cell differentiation in thymus
- adrenal gland development
- anatomical structure development
- androgen biosynthetic process
more... - anterior/posterior pattern specification
- axis specification
- branching involved in ureteric bud morphogenesis
- branching morphogenesis of a tube
- canonical Wnt receptor signaling pathway
- cell differentiation
- cell fate commitment
- cellular response to estradiol stimulus
- cellular response to hydrostatic pressure
- cellular response to transforming growth factor beta stimulus
- dermatome development
- embryonic epithelial tube formation
- endoderm development
- epithelial to mesenchymal transition
- establishment of protein localization in plasma membrane
- female gonad development
- female sex determination
- gamete generation
- hormone metabolic process
- immature T cell proliferation in thymus
- kidney development
- liver development
- male gonad development
- mammary gland epithelium development
- mesenchymal to epithelial transition
- mesonephric tubule development
- mesonephros development
- metanephric nephron morphogenesis
- metanephros development
- negative regulation of apoptosis
- negative regulation of canonical Wnt receptor signaling pathway
- negative regulation of cell differentiation
- negative regulation of fibroblast growth factor receptor signaling pathway
- negative regulation of gene expression
- negative regulation of male gonad development
- negative regulation of steroid biosynthetic process
- negative regulation of testicular blood vessel morphogenesis
- negative regulation of testosterone biosynthetic process
- negative regulation of transcription, DNA-dependent
- non-canonical Wnt receptor signaling pathway
- oocyte development
- paramesonephric duct development
- positive regulation of aldosterone biosynthetic process
- positive regulation of bone mineralization
- positive regulation of canonical Wnt receptor signaling pathway
- positive regulation of collagen biosynthetic process
- positive regulation of cortisol biosynthetic process
- positive regulation of meiosis
- positive regulation of osteoblast differentiation
- positive regulation of transcription, DNA-dependent
- protein palmitoylation
- regulation of cell-cell adhesion
- renal vesicle formation
- renal vesicle induction
- response to estradiol stimulus
- sex differentiation
- smooth muscle cell differentiation
- somatotropin secreting cell differentiation
- tertiary branching involved in mammary gland duct morphogenesis
- thyroid-stimulating hormone-secreting cell differentiation
- tube morphogenesis
less...
|
| | molecular_function | - G-protein-coupled receptor binding
- frizzled binding
- molecular_function
- transcription corepressor activity
more...
|
| |
Col15a1 | 2 |
BP MF CC |
| cellular_component | - basement membrane
- extracellular matrix
- extracellular space
|
| | |
S100a8 | 2 |
BP MF CC |
| cellular_component | - cytoplasm
- cytoskeleton
- extracellular region
- extracellular space
more... - plasma membrane
less...
|
| molecular_function | - calcium ion binding
- molecular_function
|
| |
Cd72 | 2 |
BP MF CC |
| cellular_component | - integral to plasma membrane
|
| | |
Gadd45a | 2 |
BP MF CC |
biological_process | - G2/M transition of mitotic cell cycle
- cell cycle arrest
- cellular response to ionizing radiation
- cellular response to mechanical stimulus
more... - centrosome cycle
- negative regulation of protein kinase activity
- positive regulation of reactive oxygen species metabolic process
- regulation of cell cycle
- response to DNA damage stimulus
- signal transduction in response to DNA damage
less...
|
| | | |
Ahr | 2 |
BP MF CC |
biological_process | - apoptosis
- cell cycle
- cellular response to glucocorticoid stimulus
- gland development
more... - intracellular receptor mediated signaling pathway
- negative regulation of transcription from RNA polymerase II promoter
- ovarian follicle development
- positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
- positive regulation of transcription, DNA-dependent
- prostate gland development
- regulation of B cell proliferation
- regulation of gene expression
- regulation of transcription from RNA polymerase II promoter
- regulation of transcription, DNA-dependent
- reproductive structure development
- response to estradiol stimulus
- response to organic cyclic compound
- response to stress
- response to xenobiotic stimulus
- signal transduction
- transcription from RNA polymerase II promoter
- transcription, DNA-dependent
less...
|
| cellular_component | - cytoplasm
- cytosol
- nucleolus
- nucleus
more...
|
| molecular_function | - DNA binding
- Hsp90 protein binding
- aryl hydrocarbon receptor activity
- ligand-dependent nuclear receptor activity
more... - protein binding
- protein heterodimerization activity
- receptor activity
- sequence-specific DNA binding
- sequence-specific DNA binding transcription factor activity
- sequence-specific distal enhancer binding RNA polymerase II transcription factor activity
- signal transducer activity
- transcription factor binding
- transcription regulatory region DNA binding
less...
|
| |
Lbp | 2 |
BP MF CC |
biological_process | - acute-phase response
- cellular response to lipopolysaccharide
- cellular response to lipoteichoic acid
- defense response to Gram-negative bacterium
more... - defense response to Gram-positive bacterium
- detection of molecule of bacterial origin
- innate immune response
- leukocyte chemotaxis involved in inflammatory response
- lipid transport
- lipopolysaccharide transport
- lipopolysaccharide-mediated signaling pathway
- macrophage activation involved in immune response
- negative regulation of growth of symbiont in host
- negative regulation of tumor necrosis factor production
- positive regulation of chemokine production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of macrophage activation
- positive regulation of neutrophil chemotaxis
- positive regulation of respiratory burst involved in inflammatory response
- positive regulation of toll-like receptor 4 signaling pathway
- positive regulation of tumor necrosis factor biosynthetic process
- positive regulation of tumor necrosis factor production
- response to lipopolysaccharide
- transport
less...
|
| cellular_component | - extracellular region
- extracellular space
|
| | |
Cd2 | 2 |
BP MF CC |
biological_process | - T cell activation
- cell adhesion
- cell-cell adhesion
|
| | | |
Ccl4 | 2 |
BP MF CC |
biological_process | - chemotaxis
- immune response
- inflammatory response
- regulation of vascular permeability
more...
|
| cellular_component | - extracellular region
- extracellular space
- soluble fraction
|
| | |
Tnfrsf11b | 2 |
BP MF CC |
biological_process | - apoptosis
- extracellular matrix organization
- negative regulation of bone resorption
- negative regulation of odontogenesis of dentine-containing tooth
more... - negative regulation of osteoclast differentiation
- response to arsenic-containing substance
- response to drug
- response to estrogen stimulus
- response to inorganic substance
- response to magnesium ion
- response to nutrient
- signal transduction
less...
|
| cellular_component | - extracellular region
- extracellular space
- proteinaceous extracellular matrix
|
| | |
Ace | 2 |
BP MF CC |
biological_process | - arachidonic acid secretion
- eating behavior
- heart contraction
- hormone catabolic process
more... - kidney development
- neutrophil mediated immunity
- peptide catabolic process
- peptide metabolic process
- positive regulation of apoptosis
- positive regulation of inflammatory response
- positive regulation of neurogenesis
- proteolysis
- regulation of blood pressure
- regulation of smooth muscle cell migration
- response to hypoxia
- response to lipopolysaccharide
- response to nutrient levels
- sensory perception of pain
- vasoconstriction
less...
|
| | molecular_function | - actin binding
- bradykinin receptor binding
- carboxypeptidase activity
- chloride ion binding
more... - drug binding
- metal ion binding
- metallopeptidase activity
- peptidase activity
- peptide binding
- peptidyl-dipeptidase activity
- zinc ion binding
less...
|
| |
Pold4 | 2 |
BP MF CC |
biological_process | - DNA-dependent DNA replication
- nucleotide-excision repair, DNA gap filling
- positive regulation of endothelial cell proliferation
|
| cellular_component | - delta DNA polymerase complex
- nucleoplasm
- nucleus
|
| | |
Fmo5 | 2 |
BP MF CC |
| cellular_component | - endoplasmic reticulum
- integral to membrane
- intrinsic to endoplasmic reticulum membrane
- membrane
more... - microsome
less...
|
| molecular_function | - NADP binding
- flavin adenine dinucleotide binding
- flavin-containing monooxygenase activity
- monooxygenase activity
more...
|
| |
Itgb2 | 2 |
BP MF CC |
biological_process | - activated T cell proliferation
- cell adhesion
- cell-cell adhesion
- cell-matrix adhesion
more... - cellular extravasation
- endothelial cell migration
- integrin-mediated signaling pathway
- leukocyte cell-cell adhesion
- leukocyte migration involved in inflammatory response
- multicellular organismal development
- natural killer cell activation
- neutrophil chemotaxis
- positive regulation of NF-kappaB transcription factor activity
- positive regulation of angiogenesis
- positive regulation of nitric oxide biosynthetic process
- regulation of peptidyl-tyrosine phosphorylation
less...
|
| | molecular_function | - cell adhesion molecule binding
- glycoprotein binding
- protein complex binding
- protein heterodimerization activity
more... - protein kinase binding
less...
|
| |
Ptpra | 2 |
BP MF CC |
biological_process | - insulin receptor signaling pathway
- oligodendrocyte differentiation
- peptidyl-tyrosine dephosphorylation
- positive regulation of oligodendrocyte differentiation
more... - protein phosphorylation
less...
|
| cellular_component | - integral to membrane
- microsome
- plasma membrane
- plasma membrane enriched fraction
more...
|
| molecular_function | - hydrolase activity
- protein binding
- protein complex binding
- protein tyrosine phosphatase activity
more...
|
| |
Anpep | 2 |
BP MF CC |
|
Cxcr4 | 2 |
BP MF CC |
biological_process | - G-protein coupled receptor protein signaling pathway
- T cell proliferation
- ameboidal cell migration
- brain development
more... - cardiac muscle contraction
- cell migration
- epithelial cell development
- germ cell development
- germ cell migration
- motor axon guidance
- myelin maintenance
- neural precursor cell proliferation
- neuron migration
- neuron recognition
- patterning of blood vessels
- positive regulation of oligodendrocyte differentiation
- regulation of calcium ion transport
- regulation of cell migration
- regulation of chemotaxis
- regulation of programmed cell death
- response to hypoxia
- telencephalon cell migration
less...
|
| | molecular_function | - C-C chemokine receptor activity
- C-X-C chemokine receptor activity
- G-protein coupled receptor activity
- actin binding
more... - myosin light chain binding
- receptor activity
- signal transducer activity
- ubiquitin binding
- ubiquitin protein ligase binding
less...
|
| |
Bst1 | 2 |
BP MF CC |
| cellular_component | - anchored to membrane
- cellular_component
- plasma membrane
|
| molecular_function | - NAD+ nucleosidase activity
- binding
- hydrolase activity
- molecular_function
more...
|
| |
Mmp9 | 2 |
BP MF CC |
biological_process | - aging
- anatomical structure regression
- cell growth
- cellular response to cell-matrix adhesion
more... - cellular response to cytokine stimulus
- cellular response to interleukin-1
- cellular response to low-density lipoprotein particle stimulus
- collagen catabolic process
- extracellular matrix organization
- metabolic process
- ossification
- positive regulation of angiogenesis
- positive regulation of apoptosis
- positive regulation of keratinocyte migration
- positive regulation of leukocyte migration
- positive regulation of synaptic plasticity
- proteolysis
- response to drug
- response to estradiol stimulus
- response to ethanol
- response to heat
- response to hyperoxia
- response to hypoxia
- response to lipopolysaccharide
- response to mechanical stimulus
- response to nicotine
- response to nutrient
- response to organic cyclic compound
- response to organic substance
- response to oxidative stress
- response to radiation
- response to retinoic acid
- response to tumor necrosis factor
- response to vitamin A
- skeletal system development
- tissue remodeling
- transformation of host cell by virus
less...
|
| | | |
Cp | 2 |
BP MF CC |
biological_process | - aging
- cellular iron ion homeostasis
- copper ion transport
- ion transport
more... - liver development
- lung development
- oxidation-reduction process
- plasma membrane copper ion transport
- response to copper ion
- response to nutrient
less...
|
| cellular_component | - anchored to plasma membrane
- extracellular region
- extracellular space
|
| molecular_function | - chaperone binding
- copper ion binding
- ferroxidase activity
- metal ion binding
more... - oxidoreductase activity
less...
|
| |
Col11a1 | 2 |
BP MF CC |
biological_process | - cartilage condensation
- cartilage development
- chondrocyte development
- collagen fibril organization
more... - detection of mechanical stimulus involved in sensory perception of sound
- embryonic skeletal system morphogenesis
- heart morphogenesis
- inner ear morphogenesis
- ossification
- proteoglycan metabolic process
- sensory perception of sound
- skeletal system morphogenesis
- ventricular cardiac muscle tissue morphogenesis
- visual perception
less...
|
| cellular_component | - collagen
- collagen type XI
- extracellular matrix
- extracellular region
more...
|
| molecular_function | - extracellular matrix structural constituent
|
| |
Eno2 | 2 |
BP MF CC |
| cellular_component | - cytoplasm
- insoluble fraction
- intracellular
- neuronal cell body
more... - perikaryon
- phosphopyruvate hydratase complex
- photoreceptor inner segment
- plasma membrane
- soluble fraction
- synaptosome
less...
|
| | |
Tnc | 2 |
BP MF CC |
biological_process | - bud outgrowth involved in lung branching
- cellular response to prostaglandin D stimulus
- cellular response to retinoic acid
- cellular response to vitamin D
more... - mesenchymal-epithelial cell signaling involved in prostate gland development
- negative regulation of cell adhesion
- neuromuscular junction development
- neuron projection development
- odontogenesis of dentine-containing tooth
- peripheral nervous system axon regeneration
- positive regulation of cell proliferation
- positive regulation of gene expression
- prostate gland epithelium morphogenesis
- response to ethanol
- response to fibroblast growth factor stimulus
- response to mechanical stimulus
- response to wounding
- wound healing
less...
|
| | molecular_function | - molecular_function
- syndecan binding
|
| |
Wnt2 | 2 |
BP MF CC |
biological_process | - Wnt receptor signaling pathway
- atrial cardiac muscle tissue morphogenesis
- canonical Wnt receptor signaling pathway
- cardiac epithelial to mesenchymal transition
more... - cell-cell signaling
- cellular response to transforming growth factor beta stimulus
- labyrinthine layer blood vessel development
- lung development
- lung induction
- mammary gland epithelium development
- multicellular organismal development
- positive regulation of canonical Wnt receptor signaling pathway
- positive regulation of cardiac muscle cell proliferation
- positive regulation of cell proliferation
- positive regulation of endothelial cell proliferation
- positive regulation of epithelial cell proliferation involved in lung morphogenesis
- positive regulation of fibroblast proliferation
- positive regulation of mesenchymal cell proliferation
- positive regulation of sequence-specific DNA binding transcription factor activity
- positive regulation of transcription from RNA polymerase II promoter
less...
|
| cellular_component | - cytoplasm
- extracellular matrix
- plasma membrane
|
| molecular_function | - cytokine activity
- frizzled binding
- molecular_function
|
| |
Cd53 | 2 |
BP MF CC |
| cellular_component | - cell surface
- integral to membrane
- membrane
|
| | |
Cd37 | 2 |
BP MF CC |
biological_process | - positive regulation of immunoglobulin production
- regulation of humoral immune response
|
| cellular_component | - integral to membrane
- membrane
|
| | |
Thy1 | 2 |
BP MF CC |
biological_process | - T cell receptor signaling pathway
- angiogenesis
- cell-cell adhesion
- cytoskeleton organization
more... - focal adhesion assembly
- mast cell activation
- negative regulation of T cell receptor signaling pathway
- negative regulation of apoptosis
- negative regulation of axonogenesis
- negative regulation of cell migration
- negative regulation of fibroblast proliferation
- negative regulation of protein kinase activity
- positive regulation of GTPase activity
- positive regulation of Rho GTPase activity
- positive regulation of T cell activation
- positive regulation of peptidyl-tyrosine phosphorylation
- positive regulation of release of sequestered calcium ion into cytosol
- retinal cone cell development
less...
|
| cellular_component | - anchored to external side of plasma membrane
- anchored to plasma membrane
- cell surface
- cytosol
more... - dendrite
- endoplasmic reticulum
- external side of plasma membrane
- growth cone
- membrane raft
- plasma membrane
less...
|
| | |
Fn1 | 2 |
BP MF CC |
biological_process | - acute-phase response
- angiogenesis
- anti-apoptosis
- cell adhesion
more... - cell-matrix adhesion
- cell-substrate junction assembly
- extracellular matrix organization
- ossification
- peptide cross-linking
- positive regulation of peptidase activity
- regulation of cell shape
- substrate adhesion-dependent cell spreading
- wound healing
less...
|
| | molecular_function | - extracellular matrix structural constituent
- heparin binding
- mercury ion binding
- peptidase activator activity
more... - protease binding
less...
|
| |
Prap1 | 2 |
BP MF CC |
|
Mmp11 | 2 |
BP MF CC |
biological_process | - collagen catabolic process
- proteolysis
|
| cellular_component | - extracellular region
- proteinaceous extracellular matrix
|
| molecular_function | - calcium ion binding
- metalloendopeptidase activity
- peptidase activity
- zinc ion binding
more...
|
| |
Lcp2 | 2 |
BP MF CC |
biological_process | - cytokine secretion
- mast cell activation
|
| | | |
Timp1 | 2 |
BP MF CC |
biological_process | - aging
- cartilage development
- cell activation
- erythrocyte maturation
more... - negative regulation of apoptosis
- negative regulation of membrane protein ectodomain proteolysis
- response to cytokine stimulus
- response to organic substance
- response to peptide hormone stimulus
- steroid biosynthetic process
- wound healing
less...
|
| cellular_component | - basement membrane
- extracellular matrix
- extracellular region
- proteinaceous extracellular matrix
more...
|
| molecular_function | - enzyme inhibitor activity
- metal ion binding
- metalloendopeptidase inhibitor activity
|
| |
Prkce | 2 |
BP MF CC |
biological_process | - cellular response to ethanol
- cellular response to hypoxia
- intracellular signal transduction
- lipopolysaccharide-mediated signaling pathway
more... - locomotory exploration behavior
- macrophage activation involved in immune response
- positive regulation of I-kappaB kinase/NF-kappaB cascade
- positive regulation of MAPKKK cascade
- positive regulation of catalytic activity
- positive regulation of cell-substrate adhesion
- positive regulation of insulin secretion
- positive regulation of lipid catabolic process
- positive regulation of mucus secretion
- positive regulation of synaptic transmission, GABAergic
- protein phosphorylation
- regulation of insulin secretion involved in cellular response to glucose stimulus
- regulation of lipid metabolic process
- regulation of peptidyl-tyrosine phosphorylation
- release of sequestered calcium ion into cytosol
- response to morphine
less...
|
| | molecular_function | - ATP binding
- SH3 domain binding
- calcium-independent protein kinase C activity
- enzyme activator activity
more... - enzyme binding
- ethanol binding
- metal ion binding
- nucleotide binding
- protein binding
- protein kinase C activity
- protein kinase binding
- protein serine/threonine kinase activity
- receptor activator activity
less...
|
| |
Tlr4 | 2 |
BP MF CC |
biological_process | - I-kappaB phosphorylation
- MyD88-dependent toll-like receptor signaling pathway
- MyD88-independent toll-like receptor signaling pathway
- activation of MAPK activity
more... - activation of innate immune response
- cellular response to lipopolysaccharide
- cellular response to lipoteichoic acid
- cellular response to mechanical stimulus
- defense response to Gram-negative bacterium
- defense response to bacterium
- detection of lipopolysaccharide
- immunoglobulin mediated immune response
- inflammatory response
- innate immune response
- innate immune response-activating signal transduction
- interferon-gamma production
- intestinal epithelial structure maintenance
- lipopolysaccharide-mediated signaling pathway
- macrophage activation
- microglial cell activation involved in immune response
- negative regulation of ERK1 and ERK2 cascade
- negative regulation of interferon-gamma production
- negative regulation of interleukin-17 production
- negative regulation of interleukin-23 production
- negative regulation of interleukin-6 production
- negative regulation of tumor necrosis factor production
- nitric oxide production involved in inflammatory response
- pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity
- positive regulation of B cell proliferation
- positive regulation of DNA binding
- positive regulation of ERK1 and ERK2 cascade
- positive regulation of I-kappaB kinase/NF-kappaB cascade
- positive regulation of JNK cascade
- positive regulation of MHC class II biosynthetic process
- positive regulation of NF-kappaB import into nucleus
- positive regulation of NF-kappaB transcription factor activity
- positive regulation of apoptosis
- positive regulation of chemokine production
- positive regulation of inflammatory response
- positive regulation of interferon-alpha production
- positive regulation of interferon-beta biosynthetic process
- positive regulation of interferon-beta production
- positive regulation of interferon-gamma production
- positive regulation of interleukin-1 production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 biosynthetic process
- positive regulation of interleukin-12 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 biosynthetic process
- positive regulation of interleukin-8 production
- positive regulation of lymphocyte proliferation
- positive regulation of macrophage cytokine production
- positive regulation of nitric oxide biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
- positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
- positive regulation of peptidyl-tyrosine phosphorylation
- positive regulation of platelet activation
- positive regulation of sequence-specific DNA binding transcription factor activity
- positive regulation of stress-activated MAPK cascade
- positive regulation of transcription from RNA polymerase II promoter
- positive regulation of tumor necrosis factor biosynthetic process
- positive regulation of tumor necrosis factor production
- regulation of inflammatory response
- regulation of sensory perception of pain
- response to activity
- response to bacterium
- response to ethanol
- response to fatty acid
- response to glucocorticoid stimulus
- response to hypoxia
- response to insulin stimulus
- response to lipopolysaccharide
- response to oxidative stress
- response to progesterone stimulus
- response to toxin
- signal transduction
- skeletal muscle contraction
- toll-like receptor signaling pathway
less...
|
| | | |
Bcl2a1d | 2 |
BP MF CC |
biological_process | - B cell homeostasis
- anti-apoptosis
- apoptosis
- negative regulation of apoptosis
more...
|
| | molecular_function | - BH domain binding
- protein heterodimerization activity
|
| |
C3 | 2 |
BP MF CC |
biological_process | - blood coagulation
- chemotaxis
- complement activation
- complement activation, alternative pathway
more... - complement activation, classical pathway
- inflammatory response
- positive regulation of ERK1 and ERK2 cascade
- positive regulation of activation of membrane attack complex
- positive regulation of angiogenesis
- positive regulation of developmental growth
- positive regulation of phagocytosis
- positive regulation of type IIa hypersensitivity
- positive regulation vascular endothelial growth factor production
- response to estradiol stimulus
- response to estrogen stimulus
- response to glucocorticoid stimulus
- response to magnesium ion
- response to progesterone stimulus
- tolerance induction
less...
|
| cellular_component | - extracellular region
- extracellular space
|
| molecular_function | - cofactor binding
- endopeptidase inhibitor activity
- lipid binding
- protein binding
more...
|
| |
Muc1 | 2 |
BP MF CC |
biological_process | - cellular response to retinoic acid
- epithelial cell differentiation
- female pregnancy
- response to hypoxia
more...
|
| cellular_component | - apical plasma membrane
- cell surface
- cytoplasm
- integral to membrane
more... - plasma membrane
less...
|
| | |
Rbp2 | 2 |
BP MF CC |
biological_process | - retinol metabolic process
- steroid metabolic process
|
| | molecular_function | - lipid binding
- retinal binding
- retinol binding
- transporter activity
more...
|
| |
Atf3 | 2 |
BP MF CC |
biological_process | - cell fate determination
- gluconeogenesis
- negative regulation of transcription, DNA-dependent
- positive regulation of cell proliferation
more... - regulation of transcription, DNA-dependent
- transcription, DNA-dependent
less...
|
| | | |
Il18 | 2 |
BP MF CC |
biological_process | - T-helper 1 type immune response
- angiogenesis
- cellular response to cAMP
- cellular response to hydrogen peroxide
more... - cellular response to interferon-gamma
- cellular response to lipopolysaccharide
- cellular response to mechanical stimulus
- cellular response to parathyroid hormone stimulus
- cellular response to peptide hormone stimulus
- cellular response to tumor necrosis factor
- detection of mechanical stimulus involved in sensory perception of pain
- digestive tract morphogenesis
- interferon-gamma biosynthetic process
- learning or memory
- lung development
- osteoblast differentiation
- positive regulation of NK T cell proliferation
- positive regulation of activated T cell proliferation
- positive regulation of blood vessel remodeling
- positive regulation of chemokine production
- positive regulation of collagen biosynthetic process
- positive regulation of gene expression
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of interferon-gamma production
- positive regulation of interleukin-1 beta production
- positive regulation of interleukin-17 production
- positive regulation of interleukin-8 production
- positive regulation of male germ cell proliferation
- positive regulation of natural killer cell proliferation
- positive regulation of neuron apoptosis
- positive regulation of superoxide anion generation
- positive regulation of tumor necrosis factor production
- positive regulation of vascular permeability
- regulation of cell adhesion
- regulation of circadian sleep/wake cycle, non-REM sleep
- response to cold
- response to hyperoxia
- response to hypoxia
- response to peptide hormone stimulus
- response to radiation
- sleep
less...
|
| cellular_component | - apical plasma membrane
- cytoplasm
- extracellular region
- extracellular space
more...
|
| molecular_function | - cytokine activity
- interleukin-18 receptor binding
- protein binding
|
| |
Il2rg | 2 |
BP MF CC |
| cellular_component | - cell surface
- external side of plasma membrane
- integral to membrane
- membrane
more...
|
| molecular_function | - cytokine binding
- cytokine receptor activity
- interleukin-2 binding
- interleukin-7 binding
more...
|
| |
Lamb3 | 2 |
BP MF CC |
biological_process | - biological_process
- brown fat cell differentiation
- hemidesmosome assembly
|
| cellular_component | - basement membrane
- cellular_component
- laminin-5 complex
|
| | |
Cd36 | 2 |
BP MF CC |
biological_process | - apoptotic cell clearance
- cGMP-mediated signaling
- cell adhesion
- cell surface receptor linked signaling pathway
more... - cellular response to bacterial lipopeptide
- cellular response to hydroperoxide
- cellular response to insulin stimulus
- cellular response to lipopolysaccharide
- cellular response to lipoteichoic acid
- cholesterol transport
- defense response to Gram-positive bacterium
- fatty acid metabolic process
- fatty acid oxidation
- fatty acid transport
- lipid storage
- lipoprotein transport
- long-chain fatty acid metabolic process
- long-chain fatty acid transport
- low-density lipoprotein particle clearance
- low-density lipoprotein particle mediated signaling
- negative regulation of angiogenesis
- negative regulation of gene expression
- negative regulation of growth of symbiont in host
- negative regulation of transcription factor import into nucleus
- negative regulation of transcription from RNA polymerase II promoter
- nitric oxide mediated signal transduction
- pattern recognition receptor signaling pathway
- phagocytosis, recognition
- plasma lipoprotein particle clearance
- plasma membrane long-chain fatty acid transport
- positive regulation of I-kappaB kinase/NF-kappaB cascade
- positive regulation of MAPKKK cascade
- positive regulation of blood coagulation
- positive regulation of blood microparticle formation
- positive regulation of cell-matrix adhesion
- positive regulation of cholesterol storage
- positive regulation of interleukin-12 production
- positive regulation of interleukin-6 production
- positive regulation of macrophage cytokine production
- positive regulation of macrophage derived foam cell differentiation
- positive regulation of peptidyl-tyrosine phosphorylation
- positive regulation of phagocytosis, engulfment
- positive regulation of reactive oxygen species metabolic process
- positive regulation of tumor necrosis factor production
- regulation of removal of superoxide radicals
- response to activity
- response to drug
- response to estradiol stimulus
- response to growth hormone stimulus
- response to mechanical stimulus
- response to nutrient
- transport
- triglyceride metabolic process
less...
|
| cellular_component | - Golgi apparatus
- apical part of cell
- caveola
- cell surface
more... - external side of plasma membrane
- integral to membrane
- intracellular
- membrane
- membrane raft
- microsome
- mitochondrion
- plasma membrane
- sarcolemma
less...
|
| molecular_function | - Gram-negative bacterial cell surface binding
- Gram-positive bacterial cell surface binding
- fatty acid binding
- high-density lipoprotein particle binding
more... - lipid binding
- lipoprotein particle binding
- lipoteichoic acid receptor activity
- low-density lipoprotein particle binding
- low-density lipoprotein receptor activity
- protein binding
- receptor activity
- thrombospondin receptor activity
- transforming growth factor beta binding
less...
|
| |
Junb | 2 |
BP MF CC |
biological_process | - cellular process
- cellular response to calcium ion
- cellular response to hormone stimulus
- decidualization
more... - embryonic process involved in female pregnancy
- female pregnancy
- in utero embryonic development
- labyrinthine layer blood vessel development
- osteoblast differentiation
- osteoblast proliferation
- osteoclast differentiation
- positive regulation of cell differentiation
- regulation of cell cycle
- regulation of transcription, DNA-dependent
- response to cAMP
- response to corticosterone stimulus
- response to cytokine stimulus
- response to drug
- response to light stimulus
- response to mechanical stimulus
- response to organic cyclic compound
- response to peptide hormone stimulus
- response to progesterone stimulus
- transcription from RNA polymerase II promoter
- trophectodermal cell differentiation
- vasculogenesis
less...
|
| | | |
Loxl1 | 2 |
BP MF CC |
biological_process | - oxidation-reduction process
|
| | molecular_function | - oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
|
| |
Socs3 | 2 |
BP MF CC |
biological_process | - JAK-STAT cascade
- aging
- branching involved in embryonic placenta morphogenesis
- intracellular protein kinase cascade
more... - negative regulation of insulin receptor signaling pathway
- negative regulation of signal transduction
- organ regeneration
- placenta blood vessel development
- positive regulation of cell differentiation
- regulation of cell differentiation
- regulation of cell growth
- regulation of protein phosphorylation
- response to bacterium
- response to cytokine stimulus
- response to drug
- response to estradiol stimulus
- response to food
- response to gamma radiation
- response to glucocorticoid stimulus
- response to heat
- response to hormone stimulus
- response to hypoxia
- response to insulin stimulus
- response to lipopolysaccharide
- response to organic cyclic compound
- response to peptide hormone stimulus
- response to progesterone stimulus
- signal transduction
- spongiotrophoblast differentiation
- trophoblast giant cell differentiation
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Ctgf | 2 |
BP MF CC |
biological_process | - DNA replication
- angiogenesis
- cartilage condensation
- cell adhesion
more... - cell differentiation
- cell migration
- cell-matrix adhesion
- cytosolic calcium ion transport
- extracellular matrix constituent secretion
- fibroblast growth factor receptor signaling pathway
- integrin-mediated signaling pathway
- intracellular signal transduction
- lung development
- organ senescence
- ossification
- positive regulation of G0 to G1 transition
- positive regulation of cardiac muscle contraction
- positive regulation of caspase activity
- positive regulation of cell activation
- positive regulation of cell death
- positive regulation of cell proliferation
- positive regulation of collagen biosynthetic process
- positive regulation of gene expression
- positive regulation of protein phosphorylation
- reactive oxygen species metabolic process
- regulation of cell growth
- response to amino acid stimulus
- response to anoxia
- response to estradiol stimulus
- response to fatty acid
- response to glucose stimulus
- response to mineralocorticoid stimulus
- response to organic cyclic compound
- response to peptide hormone stimulus
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| | molecular_function | - fibronectin binding
- growth factor activity
- heparin binding
- insulin-like growth factor binding
more... - integrin binding
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Lamp2 | 2 |
BP MF CC |
| cellular_component | - endosome
- endosome membrane
- integral to membrane
- late endosome
more... - lysosomal membrane
- lysosome
- membrane
- membrane fraction
- phagocytic vesicle membrane
- plasma membrane
- platelet dense granule membrane
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Rac2 | 2 |
BP MF CC |
biological_process | - GTP catabolic process
- actin cytoskeleton organization
- bone resorption
- cell projection assembly
more... - chemotaxis
- positive regulation of cell proliferation
- regulation of respiratory burst
- small GTPase mediated signal transduction
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| | molecular_function | - GTP binding
- GTPase activity
- nucleotide binding
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Il1r2 | 2 |
BP MF CC |
| cellular_component | - integral to membrane
- plasma membrane
|
| molecular_function | - interleukin-1, Type II, blocking receptor activity
- receptor activity
|
| |
Dusp1 | 2 |
BP MF CC |
biological_process | - cell cycle
- cellular response to hormone stimulus
- endoderm formation
- inactivation of MAPK activity
more... - intracellular signal transduction
- positive regulation of anti-apoptosis
- positive regulation of apoptosis
- protein dephosphorylation
- response to cAMP
- response to calcium ion
- response to estradiol stimulus
- response to glucocorticoid stimulus
- response to hydrogen peroxide
- response to light stimulus
- response to organic substance
- response to retinoic acid
- response to testosterone stimulus
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| cellular_component | - nucleoplasm
- nucleus
- soluble fraction
|
| molecular_function | - MAP kinase tyrosine/serine/threonine phosphatase activity
- hydrolase activity
- protein tyrosine phosphatase activity
- protein tyrosine/threonine phosphatase activity
more...
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| |
Src | 2 |
BP MF CC |
biological_process | - Ras protein signal transduction
- activation of protein kinase B activity
- adherens junction organization
- bone resorption
more... - branching involved in mammary gland duct morphogenesis
- cell migration
- cell proliferation
- cell-cell adhesion
- cellular membrane organization
- cellular response to fatty acid
- cellular response to hypoxia
- cellular response to insulin stimulus
- cellular response to lipopolysaccharide
- epidermal growth factor receptor signaling pathway
- forebrain development
- intracellular protein kinase cascade
- negative regulation of transcription, DNA-dependent
- nerve growth factor receptor signaling pathway
- oogenesis
- peptidyl-serine phosphorylation
- peptidyl-tyrosine phosphorylation
- phosphorylation
- platelet-derived growth factor receptor signaling pathway
- positive regulation of DNA biosynthetic process
- positive regulation of ERK1 and ERK2 cascade
- positive regulation of MAP kinase activity
- positive regulation of apoptosis
- positive regulation of canonical Wnt receptor signaling pathway
- positive regulation of cell adhesion
- positive regulation of cyclin-dependent protein kinase activity
- positive regulation of cytokine secretion
- positive regulation of gene expression
- positive regulation of glucose metabolic process
- positive regulation of insulin receptor signaling pathway
- positive regulation of intracellular protein kinase cascade
- positive regulation of phosphatidylinositol 3-kinase activity
- positive regulation of platelet-derived growth factor receptor signaling pathway
- positive regulation of protein autophosphorylation
- positive regulation of protein transport
- positive regulation of smooth muscle cell migration
- positive regulation of transcription, DNA-dependent
- protein autophosphorylation
- protein phosphorylation
- regulation of estrogen receptor signaling pathway
- response to acid
- response to drug
- response to electrical stimulus
- response to fatty acid
- response to hydrogen peroxide
- response to interleukin-1
- response to mechanical stimulus
- response to mineralocorticoid stimulus
- response to nutrient levels
- response to stress
- response to virus
- transcytosis
- uterus development
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| | molecular_function | - ATP binding
- SH2 domain binding
- cell adhesion molecule binding
- ephrin receptor binding
more... - estrogen receptor binding
- heme binding
- insulin receptor binding
- ion channel binding
- kinase activity
- non-membrane spanning protein tyrosine kinase activity
- nucleotide binding
- protein C-terminus binding
- protein binding
- protein complex binding
- protein domain specific binding
- protein kinase C binding
- protein kinase activity
- protein kinase binding
- protein tyrosine kinase activity
- receptor binding
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Selplg | 2 |
BP MF CC |
biological_process | - cellular response to interleukin-6
- leukocyte tethering or rolling
|
| | | |
Pycard | 2 |
BP MF CC |
biological_process | - activation of caspase activity
- induction of apoptosis
- inflammatory response
- interleukin-1 beta production
more... - positive regulation of NF-kappaB transcription factor activity
- positive regulation of caspase activity
- positive regulation of interleukin-1 beta secretion
- regulation of apoptosis
- regulation of cysteine-type endopeptidase activity involved in apoptotic process
- tumor necrosis factor-mediated signaling pathway
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| cellular_component | - cytoplasm
- cytoplasmic part
- cytosol
- extracellular region
more...
|
| molecular_function | - Pyrin domain binding
- protease binding
- protein homodimerization activity
|
| |
Ero1l | 2 |
BP MF CC |
| cellular_component | - endoplasmic reticulum
- endoplasmic reticulum membrane
- membrane
|
| molecular_function | - flavin adenine dinucleotide binding
- oxidoreductase activity
- oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
|
| |